| Bioactivity | MS-II-124 is an effective and selective NLRP3 inhibitor with anti-inflammatory and immunomodulatory activities, which can be used in the research of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS)[1]. |
| In Vivo | MS-II-124 (10 mg/kg; i.p.; 单剂量) 在 ALI/ARDS 野生型小鼠模型中减轻肺部炎症并减少免疫细胞的浸润，具有炎症和免疫调节活性[1]。ALI/ARDS WT C57BL/6 mice model[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 3037332-85-4 |
| Formula | C28H28ClFN2O4S |
| Molar Mass | 543.05 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xu Y, et al. Characterization of a small molecule inhibitor of the NLRP3 inflammasome and its potential use for acute lung injury[J]. Bioorganic Chemistry, 2024: 107562. |
MS-II-124
CAS: 3037332-85-4 F: C28H28ClFN2O4S W: 543.05
MS-II-124 is an effective and selective NLRP3 inhibitor with anti-inflammatory and immunomodulatory activities, which ca
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