| Bioactivity | MG-B-28 is an inhibitor of BTLA-HVEM with an IC50 value of 906 nM. MG-B-28 promotes T-cell activation in a dose-dependent manner by blocking the BTLA-HVEM interaction[1]. |
| Target | IC50: 906 nM (BTLA-HVEM) . |
| Formula | C28H25N5O3 |
| Molar Mass | 479.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Abdel-Rahman S A, et al. Small molecules from antibody pharmacophores (SMAbPs) as a hit identification workflow for immune checkpoints[J]. Science Advances, 2024, 10(42): eadq5540. |