| Bioactivity | UMB24 is a potent antagonist of σ2 receptor, with the Ki of 170 nM anf 322 nM for σ2 receptor and σ1 receptor, respectively. UMB24 attenuats cocaine-induced convulsions and locomotor activity, but not lethality[1]. |
| CAS | 1033-69-8 |
| Formula | C17H21N3 |
| Molar Mass | 267.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rae R Matsumoto, et al. Effects of UMB24 and (±)-SM 21, putative σ2-preferring antagonists, on behavioral toxic and stimulant effects of cocaine in mice. Pharmacol Biochem Behav. 2007 Jan;86(1):86-91. |