| Bioactivity | Larazotide acetate is a peptide which is an orally active zonulin antagonist. Larazotide acetate shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively. Larazotide acetate can be used for the research of celiac disease and infection. | ||||||
| Invitro | Larazotide acetate (1-100 μM; 5 d) affects Vero cell growth[1].Larazotide acetate (1-100 μM; 3 d) shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively[1].Larazotide acetate (1 and 3 mM; 72 h) inhibits cytokine-induced tight junction permeability in Caco-2 cells[2].Larazotide acetate (12.5 mM; 1 h) inhibits PTG-induced ZO-1 redistribution and actin cytoskeletal rearrangement in IEC6 cells[2]. Cell Cytotoxicity Assay[1] Cell Line: | ||||||
| Name | Larazotide acetate | ||||||
| CAS | 881851-50-9 | ||||||
| Formula | C34H59N9O12 | ||||||
| Molar Mass | 785.89 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Larazotide acetate
CAS: 881851-50-9 F: C34H59N9O12 W: 785.89
Larazotide acetate is a peptide which is an orally active zonulin antagonist. Larazotide acetate shows antiviral activit
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