| Bioactivity | LTB4 antagonist 1, a carboxamide-acid compound, is a potent Leukotriene B4 (LTB4) antagonist with an IC50 of 288 nM. LTB4 antagonist 1 has significant anti-inflammatory properties[1]. |
| In Vivo | LTB4 antagonist 1 (化合物 24b; 30 mg/kg; 口服) 在大鼠角叉菜胶足足水肿模型中，给药 1 小时后具有显着的抗炎活性[1]。 Animal Model: |
| Name | LTB4 antagonist 1 |
| Formula | C26H23NO6 |
| Molar Mass | 445.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Latifa Bouissane, et al. New and promising type of leukotriene B4 (LTB4) antagonists based on the 1,4-benzodioxine structure. Eur J Med Chem. 2023 Apr 6;254:115332. |