| Bioactivity | TSC24, a thiosemicarbazone, is a potent cruzipain (CZP) inhibitor with an IC50 of 2.86 nM, a pIC50 of 8.54 and a pKa of 8.6. TSC24 has the potential for parasitic diseases research[1]. |
| Name | TSC24 |
| Formula | C15H20Cl2N4S |
| Molar Mass | 359.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gabriel Jasinski, et al. Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors. Eur J Med Chem. 2023 Apr 7;254:115345. |