Bioactivity | L-648051 is a leukotriene D4 receptor (LTD4) antagonist. L-648051 plays an important role in arrhythmias[1]. |
In Vivo | L-648051 (5-10 mg/kg;静脉注射;一次) 可显著预防心室颤动的发生[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
CAS | 91541-18-3 |
Formula | C24H28O8S |
Molar Mass | 476.54 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. S Gök, et al. Effects of a leukotriene D4 receptor antagonist, L-648,051, and a dual inhibitor lypoxygenase and cyclooxygenase, BW-755C, on digoxin-induced arrhythmias in guinea-pigs. Arch Int Pharmacodyn Ther. 1993 Jan-Feb:321:72-80. |