| Bioactivity | JJKK 048 is an ultrapotent and highly selective inhibitor of Monoacylglycerol lipase (MAGL). | |||||||||
| Target | MAGL | |||||||||
| Name | JJKK 048 | |||||||||
| CAS | 1515855-97-6 | |||||||||
| Formula | C23H22N4O5 | |||||||||
| Molar Mass | 434.44 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Aaltonen N, et al. In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048). J Pharmacol Exp Ther. 2016 Oct;359(1):62-72. [2]. Aaltonen N, et al. Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase. Chem Biol. 2013 Mar 21;20(3):379-90. |