| Bioactivity | Clidinium bromide is a quaternary amine antimuscarinic agent. Clidinium bromide may help symptoms of cramping and abdominal/stomach pain by decreasing stomach acid, and slowing the intestines in vivo[1]. |
| In Vivo | Clidinium (oral gavage; 0.25, 0.5, and 1 mg/kg; 3 days) causes constipation in mice. It leads to a significant decrease in %transit after clidinium treatment [(F(3, 28)=27.405] in mice[1].Clidinium (oral gavage; 0.25, 0.5, and 1 mg/kg; 3 days) has a significant effect on the clonic seizure threshold induced by intravenous PTZ which received clidinium (0.25, 0.5, and 1 mg/kg) [(F(3, 35) = 14.103][1]. Animal Model: |
| Name | Clidinium bromide |
| CAS | 3485-62-9 |
| Formula | C22H26BrNO3 |
| Molar Mass | 432.35 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Leila Moezi, et al. Constipation Enhances the Propensity to Seizure in Pentylenetetrazole-Induced Seizure Models of Mice. Epilepsy Behav |
Clidinium bromide
CAS: 3485-62-9 F: C22H26BrNO3 W: 432.35
Clidinium bromide is a quaternary amine antimuscarinic agent. Clidinium bromide may help symptoms of cramping and abdomi
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