| Bioactivity | Chloralose (α-Chloralose) is a central nervous system depressant. Chloralose (α-Chloralose) allosterically modulates GABAA receptor activity and binds to a site on the GABAA receptor complex, neurosteroid, and barbiturate sites[1]. | ||||||||||||
| Target | EC50: 49 μM (GABA receptor) | ||||||||||||
| Invitro | Chloralose (α-Chloralose) activates the gama-aminobutyric acid (GABA)-induced chloride conductance of gama-aminobutyric acidA (GABAA) receptors expressed in Xenopus laevis oocytes with an EC50 value of 49 μM[1] | ||||||||||||
| Name | Chloralose | ||||||||||||
| CAS | 15879-93-3 | ||||||||||||
| Formula | C8H11Cl3O6 | ||||||||||||
| Molar Mass | 309.53 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Garrett KM, et al. Enhancement of gamma-aminobutyric acidA receptor activity by alpha-chloralose.J Pharmacol Exp Ther. 1998 May;285(2):680-6. |
Chloralose
CAS: 15879-93-3 F: C8H11Cl3O6 W: 309.53
Chloralose (α-Chloralose) is a central nervous system depressant. Chloralose (α-Chloralose) allosterically modulates G
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