Bioactivity | HIV-1 protease-IN-12 (compound 35b) is a HIV-1 protease inhibitor with an IC50 of 0.51 nM. HIV-1 protease-IN-12 also inhibits drug-resistant variant[1]. |
Name | HIV-1 protease-IN-12 |
CAS | 2925287-59-6 |
Formula | C25H35N3O5S |
Molar Mass | 489.63 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Huiyu Zhou, et al. Design, synthesis, and biological evaluation of novel HIV-1 protease inhibitors containing pyrrolidine-derived P2 ligands to combat drug-resistant variant. Eur J Med Chem. 2023 Jul 5;255:115389. |