| Bioactivity | WM-586 is a covalent WDR5 inhibitor that disrupts the binding of WDR5 to MYC. WM-586 specifically decreases cellular WDR5 and MYC interaction with the IC50 of 101 nM in HTRF assay[1]. |
| Target | IC50: 101 nM (WDR5 and MYC interaction) |
| Name | WM-586 |
| CAS | 2894832-05-2 |
| Formula | C20H20F3N5O3S |
| Molar Mass | 467.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ding J, et al. Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. ACS Chem Biol. 2023 Jan 20;18(1):34-40. |
WM-586
CAS: 2894832-05-2 F: C20H20F3N5O3S W: 467.46
WM-586 is a covalent WDR5 inhibitor that disrupts the binding of WDR5 to MYC. WM-586 specifically decreases cellular WDR
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.