| Bioactivity | Piriprost (U-60,257B) potassium is an inhibitor of leukotriene synthesis. Piriprost potassium inhibits the release of both leukotriene and histamine with an IC50 of 0.11 μM from isolated porcine lung cells. Piriprost potassium increases alkaline phosphatase (ALP) activity in cultured endometrial stromal cells[1][2]. |
| Target | IC50: 0.11 μM (leukotriene) |
| Name | Piriprost potassium |
| CAS | 88851-62-1 |
| Formula | C26H34KNO4 |
| Molar Mass | 463.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cejic SS, Kennedy TG. Examination of the effects of piriprost (U-60,257B) on alkaline phosphatase activity of rat endometrial stromal cells in vitro. Prostaglandins. 1991 Aug;42(2):179-89. [2]. McCormack DG, Paterson NA. The contrasting influence of two lipoxygenase inhibitors on hypoxic pulmonary vasoconstriction in anesthetized pigs. Am Rev Respir Dis. 1989 Jan;139(1):100-5. |
Piriprost potassium
CAS: 88851-62-1 F: C26H34KNO4 W: 463.65
Piriprost (U-60,257B) potassium is an inhibitor of leukotriene synthesis. Piriprost potassium inhibits the release of bo
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