| Bioactivity | GAD65(247-266) epitope TFA is the T cell epitopes of islet antigens，binding to I-Ag7 (type I diabetes-associated molecule) competitively with poor affinity. GAD65 refers to Glutamic Acid Decarboxylase 65，involved in the conversion of glutamate to gamma-aminobutyric acid (GABA)[1]. | ||||||
| Name | GAD65(247-266) epitope TFA | ||||||
| Sequence | Asn-Met-Tyr-Ala-Met-Met-Ile-Ala-Arg-Phe-Lys-Met-Phe-Pro-Glu-Val-Lys-Glu-Lys-Gly | ||||||
| Shortening | NMYAMMIARFKMFPEVKEKG | ||||||
| Formula | C111H174F3N27O29S4 | ||||||
| Molar Mass | 2535.99 | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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| Reference | [1]. Hausmann DH, et al. pH-dependent peptide binding properties of the type I diabetes-associated I-Ag7 molecule: rapid release of CLIP at an endosomal pH. J Exp Med. 1999 Jun 7;189(11):1723-34. |
GAD65(247-266) epitope TFA
CAS: F: C111H174F3N27O29S4 W: 2535.99
GAD65(247-266) epitope TFA is the T cell epitopes of islet antigens，binding to I-Ag7 (type I diabetes-associated molecu
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