| Bioactivity | SRE-II, an amide derivative, is an activatable photosensitizer for photodynamic cancer research with decreased fluorescence and photosensitizing capabilities. SRE-II can be further converted into the active photosensitizer SDU Red via carboxylesterase-catalyzed amide bond cleavage. SRE-II induces DNA damage and cell apoptosis in the presence of light. SRE-II can act as a promising theranostic agent for triple-negative breast cancer[1]. |
| Name | SRE-II |
| Formula | C15H9ClINO2 |
| Molar Mass | 397.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Qiaoyun Jiang, et al. Lysosome-targeting phenalenones as efficient type I/II photosensitizers for anticancer photodynamic therapy. Eur J Med Chem. 2023 Jul 5;255:115418. |