| Bioactivity | Endomorphin 1 acetate, a high affinity, highly selective agonist of the μ-opioid receptor (Ki: 1.11 nM), displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Endomorphin 1 acetate has antinociceptive properties[1][2][4]. | ||||||
| Invitro | Endomorphin 1 acetate inhibits Forskolin (HY-15371) (1 μM) stimulated cyclic AMP formation with a pIC50 value of 8.03 in In CHOμ cells[5].Endomorphin 1 (1-10 μM) acetate increases interleukin-8 secretion in Caco-2 cells[6].Endomorphin 1 (1 μM) acetate inhibits excitatory transmission in adult rat substantia gelatinosa neurons[7]. | ||||||
| Name | Endomorphin 1 acetate | ||||||
| CAS | 1276123-71-7 | ||||||
| Formula | C36H42N6O7 | ||||||
| Molar Mass | 670.75 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
Endomorphin 1 acetate
CAS: 1276123-71-7 F: C36H42N6O7 W: 670.75
Endomorphin 1 acetate, a high affinity, highly selective agonist of the μ-opioid receptor (Ki: 1.11 nM), displays reaso
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