| Bioactivity | Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1]. |
| Invitro | Eeutheroside B1 (100 µg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells[1]. RT-PCR[1] Cell Line: |
| Name | Eleutheroside B1 |
| CAS | 16845-16-2 |
| Formula | C17H20O10 |
| Molar Mass | 384.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Eleutheroside B1
CAS: 16845-16-2 F: C17H20O10 W: 384.33
Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value o
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