Bioactivity | Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy[1]. |
Invitro | Norswertianin (12.5-50 µM; 48 hours) stimulats expression of GFAP and β-tubulin in U251 cells[1].Norswertianin (40 µM; 48 hours) causes the appearance of elongated processes in U251 cells, associated with G2/M cell cycle arrest[1].Norswertianin (40 µM; 48 hours) exhibits an increase in intracellular acidification and LC3 conversion[1]. |
Name | Norswertianin |
CAS | 22172-15-2 |
Formula | C13H8O6 |
Molar Mass | 260.20 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |