| Bioactivity | 2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB[1][2][3]. |
| Invitro | 2-Hydroxychalcone inhibits invasion of triple negative breast cancer cells[1].2-hydroxychalcone inhibits the adhesion of peripheral neutrophils to the endothelial cell monolayers by inhibiting the expression of ICAM-1, VCAM-1, and E-selectin in a concentration-dependent manner[2]. |
| Name | 2-Hydroxychalcone |
| CAS | 644-78-0 |
| Formula | C15H12O2 |
| Molar Mass | 224.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
2-Hydroxychalcone
CAS: 644-78-0 F: C15H12O2 W: 224.25
2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induce
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