| Bioactivity | Efflux inhibitor-1 (compound 2) is a pyrazolo[1,5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC50s of 0.45 μM and 2.17 μM, respectively[1]. | |||||||||
| Target | IC50: 0.45 μM (ABCG2/BCRP), 2.17 μM (ABCB1) | |||||||||
| Name | Efflux inhibitor-1 | |||||||||
| CAS | 1776055-29-8 | |||||||||
| Formula | C28H25N5O3 | |||||||||
| Molar Mass | 479.53 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Larson, et al. Selective efflux inhibitors and related pharmaceutical compositions and methods of treatment: United States, US9056111[P]. 2015-06-16. |
Efflux inhibitor-1
CAS: 1776055-29-8 F: C28H25N5O3 W: 479.53
Efflux inhibitor-1 (compound 2) is a pyrazolopyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward
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