PeptideDB

ELQ-650

CAS: 3023710-00-8 F: C24H17F4NO3 W: 443.39

ELQ-650 is a quinolone derivative, that exhibits antimicrobial activity against several protozoan parasites, including t
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Bioactivity ELQ-650 is a quinolone derivative, that exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-650 attenuates babesiosis in immunosuppressed mice[1].
Invitro ELQ-650 (1 nM-1 μM, 62 h) 抑制 B. duncani 寄生虫的生长,IC50 为 22 nM,并且对人源细胞系 HeLa,HepG2,HEK293 和 HCT116 显示低毒性,IC50 平均值为 26 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> ELQ-650 相关抗体:
CAS 3023710-00-8
Formula C24H17F4NO3
Molar Mass 443.39
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Vydyam P, et al., Effectiveness of Two New Endochin-like Quinolones, ELQ-596 and ELQ-650, in Experimental Mouse Models of Human Babesiosis. ACS Infect Dis. 2024 Apr 12;10(4):1405-1413.