Bioactivity | Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma[1][2]. |
Invitro | 为了激活 Ag,用 Disomotide (G209-2M; 1 μM) 处理 PBMCs 6天[2]。 |
Name | Disomotide |
CAS | 181477-43-0 |
Sequence | Ile-Met-Asp-Gln-Val-Pro-Phe-Ser-Val |
Shortening | IMDQVPFSV |
Formula | C47H74N10O14S |
Molar Mass | 1035.21 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yang S, et al. Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J Immunol. 2002 Jul 1;169(1):531-9. [2]. Ahmadzadeh M, et al. IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother. 2007 Apr;30(3):294-302. |