PeptideDB

Disomotide

CAS: 181477-43-0 F: C47H74N10O14S W: 1035.21

Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing nat
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma[1][2].
Invitro 为了激活 Ag,用 Disomotide (G209-2M; 1 μM) 处理 PBMCs 6天[2]。
Name Disomotide
CAS 181477-43-0
Sequence Ile-Met-Asp-Gln-Val-Pro-Phe-Ser-Val
Shortening IMDQVPFSV
Formula C47H74N10O14S
Molar Mass 1035.21
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Yang S, et al. Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J Immunol. 2002 Jul 1;169(1):531-9. [2]. Ahmadzadeh M, et al. IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother. 2007 Apr;30(3):294-302.