| Bioactivity | Anti-Human IL-17A is a fully human anti-interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis[1]. |
| Target | IL-17A |
| Invitro | IL-17A 是一种介导炎症反应的细胞因子，由 T 淋巴细胞和其他免疫细胞产生。它在多种炎症性疾病中起着重要作用，例如类风湿性关节炎、银屑病、炎症性肠病等。IL-17A 通过刺激靶细胞产生促炎症细胞因子，如 IL-6、IL-8、G-CSF 等，从而引发炎症反应。 |
| Name | Anti-Human IL-17A |
| CAS | 1229022-83-6 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Reich K, et al. Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, exhibits minimal immunogenicity in patients with moderate-to-severe plaque psoriasis. Br J Dermatol. 2017 Mar;176(3):752-758. |