| Bioactivity | D-myo-Inositol-1,4,5-triphosphate sodium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum. |
| Invitro | Second messenger D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3) is served as an inositol phosphate derivative. The dissociation constant (KD) for Pr55Gag complexed with D-myo-Inositol 1,4,5-trisphosphate (an inositol with divalent phosphate groups and devoid of lipid groups) is 2170 μM. The binding affinities of D-myo-Inositol 1,4,5-trisphosphate (KD=568 μM) and 1,3,4,5-IP4 (KD=526 μM) for matrix (MA) are almost identical[1]. |
| Name | D-myo-Inositol-1,4,5-triphosphate trisodium |
| CAS | 141611-10-1 |
| Formula | C6H12Na3O15P3 |
| Molar Mass | 486.04 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Anraku K, et al. Highly sensitive analysis of the interaction between HIV-1 Gag and phosphoinositide derivatives based on surface plasmon resonance. Biochemistry. 2010 Jun 29;49(25):5109-16. |
D-myo-Inositol-1,4,5-triphosphate trisodium
CAS: 141611-10-1 F: C6H12Na3O15P3 W: 486.04
D-myo-Inositol-1,4,5-triphosphate sodium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3
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