Bioactivity | DAC-2-25 is a molecule that causes a homeotic transformation of body column into tentacle zone[1]. |
Invitro | DAC-2-25 (5 μM) 在 H. vulgaris polyps 再生的口腔末端产生额外的触须[1]。长期暴露于 DAC-2-25 (5 μM; 3 weeks) 导致异位触须形成,向息肉流产端扩散[1]。DAC-2-25 以细胞自主的方式靶向外胚层上皮细胞[1]。DAC-2-25 (5 μM; 27 days) 将体柱转变为触手区[1]。 |
Name | DAC-2-25 |
CAS | 1675245-09-6 |
Formula | C14H16N2O |
Molar Mass | 228.29 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Glauber KM, et al. A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra. Development. 2013 Dec;140(23):4788-96. |