| Bioactivity | Cyclothiazide, a positive allosteric modulator of AMPA receptors, is used frequently to block the desensitization of both native and heterologously expressed AMPA receptors. Cyclothiazide is known to produce a fast inhibition of AMPA receptor desensitization and a much slower potentiation of the AMPA current[1]. | ||||||||||||
| Name | Cyclothiazide | ||||||||||||
| CAS | 2259-96-3 | ||||||||||||
| Formula | C14H16ClN3O4S2 | ||||||||||||
| Molar Mass | 389.88 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Fucile S, et al. Effects of cyclothiazide on GluR1/AMPA receptors. Proc Natl Acad Sci U S A. 2006;103(8):2943-2947. |
Cyclothiazide
CAS: 2259-96-3 F: C14H16ClN3O4S2 W: 389.88
Cyclothiazide, a positive allosteric modulator of AMPA receptors, is used frequently to block the desensitization of bot
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