| Bioactivity | Clausine E, a alkaloid from Clausena excavata, is a inhibitor of fat mass and obesity-associated protein (FTO) demethylase. Clausine E shows inhibitory activities against proliferation of synoviocytes and cancer cells. |
| Name | Clausine E |
| CAS | 182261-83-2 |
| Formula | C14H11NO3 |
| Molar Mass | 241.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang Y, Li J, Han X, et al. Identification of Clausine E as an inhibitor of fat mass and obesity-associated protein (FTO) demethylase activity. J Mol Recognit. 2019;32(10):e2800. [2]. Guo JM, Yu XM, Jiang B, et al. Zhongguo Zhong Yao Za Zhi. 2021;46(17):4438-4445. [3]. Liger F, Popowycz F, Besson T, Picot L, Galmarini CM, Joseph B. Synthesis and antiproliferative activity of clausine E, mukonine, and koenoline bioisosteres. Bioorg Med Chem. 2007;15(16):5615-5619. |
Clausine E
CAS: 182261-83-2 F: C14H11NO3 W: 241.24
Clausine E, a alkaloid from Clausena excavata,is a inhibitor of fat mass and obesity-associated protein (FTO) demethylas
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