| Bioactivity | ChoKα inhibitor-3 is a sulphur-containing choline kinase inhibitor. ChoKα inhibitor-3 can inhibit HChoK α1 with an IC50 value of 0.66 μM. ChoKα inhibitor-3 also can induce apoptosis. ChoKα inhibitor-3 can be used for the research of cancer[1]. |
| Invitro | ChoKα inhibitor-3 (PL 48) 具有 HChoK α1 抑制活性，IC50 值为 0.66 μM[1]。ChoKα inhibitor-3 (1.46 μM; 72 h) 可抑制 A549、HeLa、HT-29 和 MCF7 细胞的增殖，IC50 值分别为 0.53 μM、0.26 μM、3.0 μM 和 1.34 μM[1].ChoKα inhibitor-3 (1, 5 μM; 48, 72 h) 可通过线粒体途径诱导癌细胞凋亡[1]。 Cell Proliferation Assay[1] Cell Line: |
| Name | ChoKα inhibitor-3 |
| Formula | C50H54Br2Cl2N4S2 |
| Molar Mass | 1005.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
ChoKα inhibitor-3
CAS: F: C50H54Br2Cl2N4S2 W: 1005.83
ChoKα inhibitor-3 is a sulphur-containing choline kinase inhibitor. ChoKα inhibitor-3 can inhibit HChoK α1 with an IC
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