Bioactivity | Carbonic anhydrase inhibitor 21 (Compound 5h) is a selective carbonic anhydrase (hCA IX) inhibitor, with a Ki of 15.1 nM, and is highly selective against other investigated isoform. Carbonic anhydrase inhibitor 21 can be used for anticancer research[1]. |
Invitro | Carbonic anhydrase inhibitor 21 抑制 hCA I, hCA II, hCA VII, hCA IX 和 hCA XIII 的 Kis 值分别为 632.8, 87.5, 42.5, 15.1, 76.4 nM[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Carbonic anhydrase inhibitor 21 相关抗体: |
Formula | C32H48N4O10P2S2 |
Molar Mass | 774.82 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sobati M, et al. Sulfonamide-incorporated bis(α-aminophosphonates) as promising carbonic anhydrase inhibitors: Design, synthesis, biological evaluation, and X-ray crystallographic studies. Arch Pharm (Weinheim). 2024 Mar 18:e2400038. |