| Bioactivity | SAHA-BPyne is an activity-based protein profiling (ABPP) probe for detecting HDAC activity, which covalently labels the proximal proteins through a photoactivation. SAHA-BPyne inhibits HDAC activity in HeLa nuclear lysate with an IC50 of less than 5 μM[1]. |
| CAS | 930772-88-6 |
| Formula | C27H31N3O5 |
| Molar Mass | 477.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Salisbury CM, et al., Optimization of activity-based probes for proteomic profiling of histone deacetylase complexes. J Am Chem Soc. 2008 Feb 20;130(7):2184-94. |
SAHA-BPyne
CAS: 930772-88-6 F: C27H31N3O5 W: 477.55
SAHA-BPyne is an activity-based protein profiling (ABPP) probe for detecting HDAC activity, which covalently labels the
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