| Bioactivity | Benalaxyl-d5is the deuterium labeledBenalaxyl(HY-121109)[1]. Benalaxyl is a fungicide, but A. fumigatus isolates are intrinsically resistant to Benalaxyl[2]. |
| Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 |
| Name | Benalaxyl-d5 |
| CAS | 2714421-66-4 |
| Formula | C20H18D5NO3 |
| Molar Mass | 330.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Meneau I, et al. Azole and fungicide resistance in clinical and environmental Aspergillus fumigatus isolates. Med Mycol. 2005 May;43 Suppl 1:S307-11. |
Benalaxyl-d5
CAS: 2714421-66-4 F: C20H18D5NO3 W: 330.43
Benalaxyl-d5is the deuterium labeledBenalaxyl(HY-121109). Benalaxyl is a fungicide, but A. fumigatus isolates are intrin
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