| Bioactivity | Biotin-labeled ODN 1018, an oligodeoxynucleotide, is a TLR-9 agonist. Biotin-labeled ODN 1018 can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy. |
| Name | Biotin-labeled ODN 1018 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Eng NF, et al. The potential of 1018 ISS adjuvant in hepatitis B vaccines: HEPLISAV™ review. Hum Vaccin Immunother. 2013 Aug;9(8):1661-72. [2]. Friedberg JW, et al. Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma. Br J Haematol. 2009 Aug;146(3):282-91. |