Bioactivity | BRD0476 is an inhibitor of pancreatic β-cell apoptosis with an EC50 value of 0.78 μM and a maximal inhibitory activity of 99%. BRD0476 can be used in diabetes-related research[1]. |
Invitro | 在细胞因子存在下,BRD0476 以剂量依赖性方式降低半胱天冬酶-3活性[1]。 |
Name | BRD0476 |
CAS | 1314958-91-2 |
Formula | C35H38N4O8S |
Molar Mass | 674.76 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chou DH, et al. Synthesis of a novel suppressor of beta-cell apoptosis via diversity-oriented synthesis. ACS Med Chem Lett. 2011 Sep 8;2(9):698-702. |