| Bioactivity | BChE-IN-4 is a potent and cross the blood-brain barrier BChE inhibitor. BChE-IN-4 attenuates learning and memory deficits caused by cholinergic deficit in mouse model. BChE-IN-4 has the potential for the research of alzheimer’s disease[1]. |
| Target | BChE |
| In Vivo | BChE-IN-4 (compound 1) (10, 20, 30 mg/kg) attenuates learning and memory deficits caused by cholinergic deficit in AD mouse model[1].BChE-IN-4 (30 mg/kg) dose not induce adverse motor effects in vivo[1]. Animal Model: |
| Name | BChE-IN-4 |
| CAS | 2304818-41-3 |
| Formula | C24H37N3O |
| Molar Mass | 383.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Meden A, et al. Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors. Eur J Med Chem. 2020 Dec 15;208:112766. |
BChE-IN-4
CAS: 2304818-41-3 F: C24H37N3O W: 383.57
BChE-IN-4 is a potent and cross the blood-brain barrier BChE inhibitor. BChE-IN-4 attenuates learning and memory deficit
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