| Bioactivity | Calpain Inhibitor XI is a reversible covalent inhibitor of calpain-1. Calpain Inhibitor XI can be used for the research of neurodegenerative disorders[1]. |
| Invitro | Calpain inhibitor XI (CaXI) (1 μM) can inhibit calpain-1, cathepsin-K and also modestly inhibits (∼20%) both papain and cathepsin-B[1]. |
| Name | Calpain Inhibitor XI |
| CAS | 145731-49-3 |
| Formula | C26H40N4O6 |
| Molar Mass | 504.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rachel C Knopp, et al. Extending the Calpain-Cathepsin Hypothesis to the Neurovasculature: Protection of Brain Endothelial Cells and Mice from Neurotrauma. ACS Pharmacol Transl Sci. 2021 Feb 2;4(1):372-385. |
Calpain Inhibitor XI
CAS: 145731-49-3 F: C26H40N4O6 W: 504.62
Calpain Inhibitor XI is a reversible covalent inhibitor of calpain-1. Calpain Inhibitor XI can be used for the research
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