| Bioactivity | Antileishmanial agent-14 is a sulfuretin analog with potential activity against the parasite Leishmania donovani promastigotes (IC50=4.1 μM). Antileishmanial agent-14 also inhibits infection by L. donovani amastigotes (IC50=11.1 μM)[1]. |
| Invitro | Antileishmanial agent-14 (compound 2o) (25 μM, 50 μM) 抑制无鞭毛体 L. donovani amastigotes 的活性，在 25 μM 和 50 μM 时抑制率分别为 116% 和 115%[1]。Antileishmanial agent-14 减少 L. donovani amastigotes 寄生虫数量，IC50 为 4.6 μM[1]。 |
| Name | Antileishmanial agent-14 |
| CAS | 1638956-72-5 |
| Formula | C23H26ClNO5 |
| Molar Mass | 431.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hassan AHE, et al. Design, synthesis, and repurposing of O6-aminoalkyl-sulfuretin analogs towards discovery of potential lead compounds as antileishmanial agents. Eur J Med Chem. 2023 May 5;251:115256. |
Antileishmanial agent-14
CAS: 1638956-72-5 F: C23H26ClNO5 W: 431.91
Antileishmanial agent-14 is a sulfuretin analog with potential activity against the parasite Leishmania donovani promast
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