| Bioactivity | Homoquinolinic acid is a non endogenous agonist of NMDAR2 receptor[1][2]. |
| Invitro | Homoquinolinic acid (HQA，20 μM) 导致在第V层记录的事件频率显著增加[2]。Homoquinolinic acid (HQA) 作用于突触前端，增强谷氨酸的释放[2]。 |
| Name | Homoquinolinic acid |
| CAS | 490-75-5 |
| Formula | C8H7NO4 |
| Molar Mass | 181.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. L P de Carvalho, et al. The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. Neurochem Int. 1996 Apr;28(4):445-52. [2]. G Woodhall, et al. NR2B-containing NMDA autoreceptors at synapses on entorhinal cortical neurons. J Neurophysiol. 2001 Oct;86(4):1644-51. |