Bioactivity | Antifungal agent 53 (A03) is a potent inhibitor of Candida albicans CYP51 with antifungal activity. Antifungal agent 53 prevents the formation of fungi biofilms. Antifungal agent 53 also exhibits good safety[1]. |
Invitro | Antifungal agent 53 (4 μg/mL;24 h) 对兔红细胞溶血作用[1] 。Antifungal agent 53 (50 μg/mL,80 μg/mL;1.5-24 h) 呈剂量依赖性抑制白色念珠菌生物膜的形成[1]。 |
Name | Antifungal agent 53 |
CAS | 2422019-76-7 |
Formula | C18H15Cl3N2Se |
Molar Mass | 444.64 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Xu H, et al. Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents. Eur J Med Chem. 2020 Jul 15;198:112360. |