| Bioactivity | Antibacterial agent 210 (compound A9), an amide derivative, is a Pseudomonas aeruginosa quorum sensing inhibitor (QSI). Antibacterial agent 210 inhibits the quorum sensing systems by binding with LasR and PqsR, especially PqsR[1]. |
| Invitro | Antibacterial agent 210 (compound A9; 160 μg/mL) 抑制铜绿假单胞菌的毒力因子。Antibacterial agent 210 显着减少 PAO1 生物膜的产生。Antibacterial agent 210 抑制铜绿假单胞菌的集群运动。Antibacterial agent 210 还抑制铜绿假单胞菌中与 QS 系统相关的基因的表达[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antibacterial agent 210 相关抗体: |
| Formula | C10H17NO |
| Molar Mass | 167.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhe He, et al. Discovery of novel amide derivatives as potent quorum sensing inhibitors of Pseudomonas aeruginosa. Eur J Med Chem. 2024 Apr 13:271:116410. |