| Bioactivity | PDGFRα/β/VEGFR-2-IN-1 (6f), a multiple PDGFRα/ß and VEGFR-2 tyrosine kinase inhibitor, particularly targets PDGFRα, PDGFRβ, and VEGFR-2 kinases with Nano molar concentrations[1]. |
| Invitro | PDGFRα/β/VEGFR-2-IN-1 (6f) 对胰腺导管腺癌MDA-PATC53和PL45细胞系是一种有效，当对正常前列腺上皮细胞 (RWPE-1) 安全性良好[1]。PDGFRα/β/VEGFR-2-IN-1 (6f) 通过上调p21并降低CDK1和cyclin B1 mRNA水平，干扰G2/M细胞周期转变[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PDGFRα/β/VEGFR-2-IN-1 相关抗体: |
| Formula | C23H16BrClN2O3 |
| Molar Mass | 483.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hend A A Ezelarab, et al. New 2-oxoindole derivatives as multiple PDGFRα/ß and VEGFR-2 tyrosine kinase inhibitors. Bioorg Chem. 2024 Apr:145:107234. |