Bioactivity | Androgen receptor antagonist 8 (Example 13) is an androgen receptor antagonist. Androgen receptor antagonist 8 inhibits prostate specific antigen secretion in LNcap cell (IC50: 88 nM). Androgen receptor antagonist 8 can be used for prostate cancer research[1]. |
Invitro | Androgen receptor antagonist 8 (Example 13) (4 days) inhibits PSA secretion in LNcap cell with an IC50 of 88 nM[1].Androgen receptor antagonist 8 (3 days) inhibits LNcap cell proliferation with an IC50 of 66 nM[1]. |
Name | Androgen receptor antagonist 8 |
CAS | 1572045-29-4 |
Formula | C22H19F4N3O4S |
Molar Mass | 497.46 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lu, Hejun, et al. Patent. Preparation of imidazoline derivatives as antiandrogens. WO2014036897. |