PeptideDB

Lipstatin

CAS: 96829-59-3 F: C29H49NO5 W: 491.70

Lipstatin is a very potent pancreatic lipase inhibitor can be isolated from Streptomyces toxytricini. Lipstatin inhibits
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Bioactivity Lipstatin is a very potent pancreatic lipase inhibitor can be isolated from Streptomyces toxytricini. Lipstatin inhibits the hydrolysis of trioleate by porcine pancreatic lipase with an IC50 of 0.14 μM[1].
In Vivo Lipstatin(20、60 mg/kg;口服;单剂量;3 天)剂量依赖性地抑制三油酸甘油酯的吸收,而油酸在小鼠体内吸收正常[1]。
Name Lipstatin
CAS 96829-59-3
Formula C29H49NO5
Molar Mass 491.70
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Weibel E K, et al. Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini I. Producing organism, fermentation, isolation and biological activity[J]. The Journal of antibiotics, 1987, 40(8): 1081-1085.