| Bioactivity | Kolavenol can be isolated from the root of Solidago altissima L. Kolavenol enantiomer has trypanocidal activity against Trypanosoma brucei rhodesiense, the causative agent of the acute form of human African trypanosomiasis, with an IC50 of 2.5 μg/ml (8.6 μM)[1][2]. |
| Name | Kolavenol |
| CAS | 19941-83-4 |
| Formula | C20H34O |
| Molar Mass | 290.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kusumoto S, et al. The Structure and the Stereochemistry of Solidagonic Acid[J]. Bulletin of the Chemical Society of Japan, 1969, 42(3): 812-820. [2]. Freiburghaus F, et al. Bioassay-guided isolation of a diastereoisomer of kolavenol from Entada abyssinica active on Trypanosoma brucei rhodesiense. J Ethnopharmacol. 1998 Jul;61(3):179-83. |