| Bioactivity | AXKO-0046 dihydrochloride, indole derivative, is an uncompetitive Lactate dehydrogenase B (LDHB) selective inhibitor. AXKO-0046 dihydrochloride has LDHB inhibitory activity with an EC50 value of 42 nM. AXKO-0046 dihydrochloride can be used for the research of cancer metabolism[1]. |
| Invitro | AXKO-0046 dihydrochloride has LDHB inhibitory activity with an EC50 value of 42 nM[1]. |
| Name | AXKO-0046 dihydrochloride |
| Formula | C25H35Cl2N3 |
| Molar Mass | 448.47 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Sachio Shibata, et al. Identification of the first highly selective inhibitor of human lactate dehydrogenase B. Sci Rep. 2021 Nov 1;11(1):21353. |
AXKO-0046 dihydrochloride
CAS: F: C25H35Cl2N3 W: 448.47
AXKO-0046 dihydrochloride, indole derivative, is an uncompetitive Lactate dehydrogenase B (LDHB) selective inhibitor. AX
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