AVLX-125

CAS: 1786434-31-8 F: C62H104N10O29 W: 1453.54

AVLX-125 (UCCB01-125) is a PSD-95 and PDZ domain inhibitor with Kd value of 10 nM. AVLX-125 can be used in the study of

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Bioactivity	AVLX-125 (UCCB01-125) is a PSD-95 and PDZ domain inhibitor with Kd value of 10 nM. AVLX-125 can be used in the study of inflammatory pain[1][2].
CAS	1786434-31-8
Sequence	Val-Asp-Thr-Glu-Ile-Ile-Glu-Thr-Asp-Val Covalent bridge:Ile5-Ile6
Shortening	VDTEIIETDV Covalent bridge:Ile5-Ile6
Formula	C62H104N10O29
Molar Mass	1453.54
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Haugaard-Kedström L M, et al. Targeting PSD-95 as a novel approach in the treatment of stroke. Neuroprotective Therapy for Stroke and Ischemic Disease, 2017: 157-184. [2]. Andreasen JT, et al. UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: comparison with the NMDA receptor antagonist MK-801. Neuropharmacology. 2013 Apr;67:193-200.