Bioactivity | API32 is a potent Pin1 inhibitor. API32 interactes with the Pin1 PPIase domain. API32 inhibits cell proliferation and migration. API32 has the potential for the research of hepatocellular carcinoma (HCC)[1]. |
CAS | 162320-41-4 |
Formula | C13H11N5O3 |
Molar Mass | 285.26 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Pu W, et al. Structure-Guided Optimization and Preclinical Evaluation of 6-O-Benzylguanine-Based Pin1 Inhibitor for Hepatocellular Carcinoma Treatment. J Med Chem. 2025 Feb 13;68(3):2869-2889. |