| Bioactivity | Biotin protein ligase-IN-1 (Compound Bio-9) is an inhibitor of biotin protein ligase (BPL) with a Kd value of 7 nM. Biotin protein ligase-IN-1 exhibits antibacterial activity, with MIC values of 0.2 and 20 μM against Staphylococcus aureus (including MRSA and MSSA) and Mycobacterium tuberculosis, respectively[1]. |
| Target | Kd: 7 nM (Biotin protein ligase). |
| Formula | C19H27N10NaO7S2 |
| Molar Mass | 594.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liu Q, et al. Metabolically Stable Adenylation Inhibitors of Biotin Protein Ligase as Antibacterial Agents. J Med Chem. 2025 Feb 13;68(3):3065-3087. |
Biotin protein ligase-IN-1
CAS: F: C19H27N10NaO7S2 W: 594.60
Biotin protein ligase-IN-1 (Compound Bio-9) is an inhibitor of biotin protein ligase (BPL) with a Kd value of 7 nM. Biot
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