Bioactivity | AK-1690 is a potent and selective STAT6 PROTAC degrader. AK-1690 reduces the levels of STAT6 protein in cells (DC50=1 nM) and depletes STAT6 protein in mouse tissues. AK-1690 can be used for the research of cancer[1]. |
CAS | 2984505-88-4 |
Formula | C51H56F2N5O11PS |
Molar Mass | 1016.05 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kaneshige A, et, al. Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader. J Med Chem. 2024 Sep 23. |