Bioactivity | AC-178335 is a SRIF antagonist, with a Ki of 172 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50=5.1 μM). AC-178335 induces GH release in anesthetized rats[1]. |
CAS | 212966-15-9 |
Sequence | Ac-{d-(His-Phe-Ile-Arg-Trp-Phe)}-NH2 |
Shortening | Ac-{d-(HFIRWF)}-NH2 |
Formula | C49H63N13O7 |
Molar Mass | 946.11 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Baumbach WR, et, al. A linear hexapeptide somatostatin antagonist blocks somatostatin activity in vitro and influences growth hormone release in rats. Mol Pharmacol. 1998 Nov;54(5):864-73. |