PeptideDB

AC-178335

CAS: 212966-15-9 F: C49H63N13O7 W: 946.11

AC-178335 is a SRIF antagonist, with a Ki of 172 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC5
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Bioactivity AC-178335 is a SRIF antagonist, with a Ki of 172 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50=5.1 μM). AC-178335 induces GH release in anesthetized rats[1].
CAS 212966-15-9
Sequence Ac-{d-(His-Phe-Ile-Arg-Trp-Phe)}-NH2
Shortening Ac-{d-(HFIRWF)}-NH2
Formula C49H63N13O7
Molar Mass 946.11
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Baumbach WR, et, al. A linear hexapeptide somatostatin antagonist blocks somatostatin activity in vitro and influences growth hormone release in rats. Mol Pharmacol. 1998 Nov;54(5):864-73.