| Bioactivity | MRX-2843 hydrochloride is an orally active, ATP-competitive dual MERTK and FLT3 tyrosine kinases inhibitor (TKI) with enzymatic IC50s of 1.3 nM for MERTK and 0.64 nM for FLT3, respectively[1]. |
| CAS | 2498541-94-7 |
| Formula | C29H43Cl3N6O |
| Molar Mass | 598.05 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Minson KA, et al. The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia. JCI Insight. 2016 Mar;1(3):e85630. |
MRX-2843 hydrochloride
CAS: 2498541-94-7 F: C29H43Cl3N6O W: 598.05
MRX-2843 hydrochloride is an orally active, ATP-competitive dual MERTK and FLT3 tyrosine kinases inhibitor (TKI) with en
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.